Wednesday, September 11, 2019

Summery of the studies been done by 3 researchers (B.K. CAMPBELL, Outline

Summery of the studies been done by 3 researchers (B.K. CAMPBELL, HELEN PICTON and MC NEILY) on folliculogenesis in Female ewes - Outline Example Concentration of FSH decreased during follicular growth, while that of LH surged. FSH concentration increased on day 1 and a second batch of follicles with 5 mm diameter emerged. The researchers concluded that preovulatory follicles emerge from large follicle population supported by FSH generation. Building up on this research, Campbell and Baird (1998) examined the antral of follicle development of genetic variation in ovulation rates for different sheep breeds. Two strategies have evolved to help achieve high fertility, the Finnish Landrace and the Fec gene, and these suppress FSH. The research indicated an unidentified gene mutation that brings this effect. An interesting research by Campbell (et al. 2000) helped to develop cortical autograft procedures to restore fertility in aged sheep. The results indicate the FSH helps to modulate folliculogenesis, and it can be used for early follicle and oocyte development. Campbell and Baird (2001) undertook a research to evaluate the local actions, the origin and control of inhibin A in sheep. The research concluded that inhibin A acts as an FSH-responsive marker of granulosa cell differentiation, and that it performs paracrine and autocrine activities. In the same years, Campbell (et al. 2001) examined the role of Booroola gene, an autosomal mutation that influences the ovulation rate, and discovered that it leads to the growth of antral follicles that increases the ovulation rate in sheep. Campbell (et al. 2003) undertook further research on the FecB Booroola gene that acts at the ovary of sheep, and enhances the sensitivity of the ovaries to stimulation. Examining the FecB (Booroola) gene, Campbell (et al. 2009) presented a paper on the mechanism of action of the FecB mutation at a conference in Pune, India. In another research, Campbell (et al. 2007) examined the use of LH on growth of large preovulatory follicles and hormone secretion in Ewes. T he study indicated that LH is required

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